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Personale dell'ISS

Marco Silano

Primo ricercatore
+39 06 4990 6001
Viale Regina Elena 299
00161 - Roma (I)
marco.silano@iss.it


Curriculum vitae

Pubblicazioni

  1. Filannino P, Cavoski I, Thlien N, Vincentini O, De Angelis M, Silano M, Gobetti M, Di Cagno R. Lactic acid fermentation of Cactus Cladodes (Opuntia ficus-indica L.) generates flavonoid derivatives with antioxidant and anti-inflammatory properties. PLoS One 2016;11(3):e0152575.
  2. Vicentini O, Maialetti F, Gonnelli E, Silano M. Gliadin-dependent cytokine production in a bidimensional cellular model of celiac intestinal mucosa. Clinical and experimental medicine 2015;15(4):447-454.
  3. Volta U, Vincentini O, Quintarelli F, Felli C, Silano M, Collaborating Centers of the Italian Registry of the Complications of Coeliac Disease. Low risk of colon cancer in patients with celiac disease. Scandinavian journal of gastroenterology 2014;49(5):564-568.
  4. Giordani L, Del Pinto T, Vincentini O, Felli C, Silano M, Viora M. Two wheat decapeptides prevent gliadin-dependent maturation of human dendritic cells. Experimental cell research 2014;321(2):248-254.
  5. Rizzello CG, Curiel JA, Nionelli L, Vincentini O, Di Cagno R, Silano M, Gobbetti M, Coda R. Use of fungal proteases and selected sourdough lactic acid bacteria for making wheat bread with an intermediate content of gluten. Food microbiology 2013;Epub 2013 Jul 5:http://dx.doi.org/10.1016/j.fm.2013.06.017.
  6. Silano M, Penas Pozo E, Uberti F, Manferdelli S, Del Pinto T, Felli C, Budelli A, Vincentini O, Restani P. Diversity of oat varieties in eliciting the early inflammatory events in celiac disease. European journal of nutrition 2013;November 2013:http://dx.doi.org/10.1007/s00394-013-0617-4.
  7. Capozzi A, Vincentini O, Gizzi P, Porzia A, Longo A, Felli C, Mattei V, Mainiero F, Silano M, Sorice M, Misasi R. Modulatory effect of gliadin peptide 10-mer on epithelial intestinal CACO-2 cell inflammatory response. PLoS One 2013;8(6):e66561.
  8. Di Simone N, De Spirito M, Di Nicuolo F, Tersigni C, Castellani R, Silano M, Maulucci G, Papi M, Scambia G, Gasbarrini A. Potential new mechanisms of placental damage in celiac disease: anti- transglutaminase antibodies impair human endometrial angiogenesis. Biology of reproduction 2013;89(4):88.
  9. Silano M, Vincentini O, Luciani A, Felli C, Caserta S, Esposito S, Villella VR, Pettoello Mantovani M, Guido S, Maiuri L. Early tissue transglutaminase-mediated response underlies K562(S)- cell gliadin-dependent agglutination. Pediatric research 2012;71(5):532-538.
  10. De Vita P, Ficco DBM, Luciani A, Vincentini O, Pettoello Mantovani M, Silano M, Maiuri L, Cattivelli L. A ?-secalin contained decamer shows a celiac disease prevention activity. Journal of cereal science 2012;55(2):234-242.
  11. Vincentini O, Quaranta MG, Viora M, Agostoni C, Silano M. Docosahexaenoic acid modulates in vitro the inflammation of celiac disease in intestinal epithelial cells via the inhibition of cPLA2. Clinical nutrition 2011;30(4):541-546.
  12. Quaranta MG, Vincentini O, Felli C, Spadaro F, Silano M, Moricoli D, Giordani L, Viora M. Exogenous HIV-1 Nef upsets the IFN-?-induced impairment of human intestinal epithelial integrity. Plos One 2011;6(8):e23442.
  13. Picarelli A, Sabbatella L, Di Tola M, Silano M, Nicolussi A, D'Inzeo S, Coppa A. Nuclear fluorescence serum reactivity on monkey oesophagus: a new antibody for the follow-up of coeliac disease? Clinical and experimental immunology 2010;161(3):417-425.
  14. Silano M, Agostoni C, Guandalini S. Effect of the timing of gluten introduction on the development of celiac disease [editorial]. World journal of gastroenterology 2010;16(16):1939-1942.
  15. Di Simone N, Silano M, Castellani R, Di Nicuolo F, D'Alessio MC, Franceschi F, Tritarelli A, Leone MA, Tersigni C, Gasbarrini G, Silveri NG, Caruso A, Gasbarrini A. Anti-tissue transglutaminase antibodies from celiac patients are responsible of throphoblast damage via apoptosis in vitro. American journal of gastroenterology 2010;105(10):2254-2261.
  16. Silano M, Volta U, De Vincenzi A, Dessì MR, De Vincenzi M, Collaborating Centers of the Italian Registry of the Complications of Coeliac Disease. Effect of gluten free diet on the risk of enteropathy-associated T-cell lymphoma in celiac disease. Digestive diseases and sciences 2008;53(4):972-976.
  17. Silano M, Di Benedetto R, Maialetti F, De Vincenzi A, Calcaterra R, Trecca A, De Vincenzi M. A 10-residue peptide from durum wheat promotes a shift from a Th1-type response towards a Th2-type response in celiac disease. American journal of clinical nutrition 2008;87(2):415-423.
  18. Silano M, Dessì MR, De Vincenzi M, Cornell Hughes J. In vitro tests indicate that certain varieties of oats may be harmful to patients with coeliac disease. Journal of gastroenterology and hepatology 2007;22(4):528-531.
  19. Silano M, Di Benedetto R, Trecca A, Arrabito G, Leonardi F, De Vincenzi M. A decapeptide from durum wheat prevents coeliac peripheral blood lymphocytes from activation by gliadin peptides. Pediatric research 2007;61(1):67-71.
  20. Silano M, Leonardi F, Trecca A, Mancini E, Di Benedetto R, De Vincenzi M. Prevention by a decapeptide from durum wheat of in vitro gliadin peptide-induced apoptosis in small-bowel mucosa from coeliac patients [letter]. Scandinavian journal of gastroenterology 2007;42(6):786-787.
  21. Silano M, Volta U, Mecchia AM, Dessì MR, Di Benedetto R, De Vincenzi M, Collaborating Centers of the Italian Registry of the Complications of Coeliac Disease. Delayed diagnosis of coeliac disease increases cancer risk. BMC gastroenterology 2007;7:8.
  22. Rizzello CG, De Angelis M, Di Cagno R, Camarca A, Silano M, Losito I, De Vincenzi M, De Bari M, Palmisano F, Maurano F, Gianfrani C, Gobbetti M. Highly efficient gluten degradation by lactobacilli and fungal proteases during food processing: new perspectives for celiac disease. Applied and environmental microbiology 2007;73(14):4499-4507.
  23. De Angelis M, Rizzello CG, Fasano A, Clemente MG, De Simone C, Silano M, De Vincenzi M, Losito I, Gobbetti M. VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for celiac sprue. Biochimica et biophysica acta. Molecular basis of disease 2006;1762(1):80-93.
  24. Silano M, De Vincenzi M. Intolleranze alimentari in età pediatrica. In: Maranghi F, Baldi F, Mantovani A, ed. Sicurezza alimentare e salute dell'infanzia. Roma: Istituto Superiore di Sanità; 2005. (Rapporti ISTISAN 05/35). p.117-120.
  25. Vincentini O, De Angelis I, Iannuccelli R, Silano M, Stammati AL, De Vincenzi M. Protective effects of mannan in caco-2/TC7 cells treated with wheat-derived peptides. Carbohydrate polymers 2005;62(4):338-343.
  26. Silano M, De Vincenzi M. Small bowel malignancy at diagnosis of coeliac disease [letter]. Gut 2005;54(4):565-566.
  27. De Vincenzi M, Stammati AL, De Vincenzi A, Silano M. Constituents of aromatic plants: carvacrol. Fitoterapia 2004;75(7-8):801-804.
  28. De Vincenzi M, De Vincenzi A, Silano M. Constituents of aromatic plants: elemicin. Fitoterapia 2004;75(6):615-618.
  29. Silano M, De Vincenzi M, De Vincenzi A, Silano V. The new European legislation on traditional herbal medicines: main features and perspectives. Fitoterapia 2004;75(2):107-116.
  30. D'Archivio M, Silano M, Fagnani C, Scazzocchio B, Nisticò L, Giovannini C, Varì R, D'Ippolito C, Cotichini R, Stazi MA, De Vincenzi M. Clinical evolution of celiac disease in Italy 1982-2002. Journal of clinical gastroenterology 2004;38(10):877-879.
  31. Silano M, Vicentini O, Muzzarelli R, Muzzarelli C, De Vincenzi M. MP-Chitosan protects CACO-2 cells from toxic gliadin peptides. Carbohydrate polymers 2004;58:215-219.
  32. De Vincenzi M, D'Archivio M, Lucchetti R, Silano M. Registro nazionale della celiachia. In: Convegno ADI Associazione italiana di dietetica e nutrizione clinica (Regione Emilia-Romagna) Problematiche clinico-terapeutico della malattia celiaca; 31 marzo 2001; 2001. p.6-nov.
  33. Picarelli A, Di Tola M, Sabbatella L, Gabrielli F, Di Cello T, Anania MC, Silano M, De Vincenzi M. Immunologic evidence of no harmful effect of oats in celiac disease 1-3. American journal of clinical nutrition 2001;74(1):137-140.
  34. Giovannini C, Sanchez M, Straface E, Scazzocchio B, Silano M, De Vincenzi M. Induction of apoptosis in Caco-2 cells by wheat gliadin peptides. Toxicology 2000;145(1):63-71.
  35. Picarelli A, Di Tola M, Sabbatella L, Anania MC, Di Cello T, Greco R, Silano M, De Vincenzi M. 31-43 amino acid sequence of the alpha-gliadin induces anti-endomysial antibody production during in vitro challenge. Scandinavian journal of gastroenterology 1999;11:1099-1102.
  36. Silano M, De Vincenzi M. Bioactive antinutritional peptides derived from cereal prolamins. Nahrung (Weinheim) 1999;43(3):175-184.
  37. Silano M, De Vincenzi M. In vitro screening of food peptides toxic for coeliac and other gluten-sensitive patients: a review. Toxicology 1999;132:99-110.
  38. De Vincenzi M, Stammati AL, Luchetti R, Silano M, Gasbarrini G, Silano V. Structural specificities and significance for coeliac disease of wheat gliadin peptides able to agglutinate or to prevent agglutination of K562(S) cells. Toxicology 1998;127(1/3):97-106.

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